FAQs About ALS

Common Questions and Answers About ALS

ALS is a disease that affects the nerve cells in both the upper and lower parts of the body. This disease causes the nerve cells to stop working and die. The nerves lose the ability to trigger specific muscles, which causes the muscles to become weak and leads to paralysis.

No one knows what causes most cases of ALS. Scientists have been studying many factors that could be linked with ALS, such as heredity and environmental exposures. Other scientists have looked at diet or injury. No cause has been found for most cases of ALS. In the future, scientists may find that many factors together cause ALS.Health studies have not found definite environmental factors that are linked with either ALS or other MNDs. Some studies suggested a possible link with exposure to heavy metals (e.g., lead and mercury). Other studies suggested a link with exposure to trace elements, solvents, radiation, and agricultural chemicals. No confirmed link was found with infections, diet, physical activity, and injury.

Although no one knows for sure, reports suggest less than 20,000 people in the United States have ALS; every year about 5,000 people are told by their doctor that they have the disease. Because no records on ALS have been kept throughout the country, it is hard to estimate the number of ALS cases in the United States. CDC does not require doctors to report ALS cases.

ALS is slightly more common in men than women, but recent studies suggest that this difference is decreasing over time. Familial ALS is equally common in men and women.

ALS is age related; most people with ALS find out they have it when they are between 55 and 75 years of age.

Most people live from 2 to 5 years after symptoms develop. How long a person lives with ALS seems to be related to age; people who are younger when the illness starts live slightly longer.